USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: UBP1_HUMAN USC-OGP 2-DE database:  UBP1_HUMAN UBP1_HUMAN General information about the entry View entry in simple text format Entry name UBP1_HUMAN Primary accession number O94782 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ubiquitin carboxyl-terminal hydrolase 1; EC=3.4.19.12 {ECO:0000269|PubMed:15694335, ECO:0000269|PubMed:16531995, ECO:0000269|PubMed:18082604, ECO:0000269|PubMed:26388029, ECO:0000269|PubMed:9806842}; AltName: Full=Deubiquitinating enzyme 1; Short=hUBP; AltName: Full=Ubiquitin thioesterase 1; AltName: Full=Ubiquitin-specific-processing protease 1;. Gene name Name=USP1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0019: pI=4.86; Mw=93911 Cross-references UniProtKB/Swiss-Prot O94782; UBP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name UBP1_HUMAN Primary accession number O94782 Secondary accession number(s) A0PJ95 D3DQ57 Q05BX7 Q59H66 Q9UFR0 Q9UNJ3 Sequence was last modified on  May 1, 1999 (version 1) Annotations were last modified on  March 15, 2017 (version 155) Name and origin of the protein Description RecName: Full=Ubiquitin carboxyl-terminal hydrolase 1; EC=3.4.19.12 {ECO:0000269|PubMed:15694335, ECO:0000269|PubMed:16531995, ECO:0000269|PubMed:18082604, ECO:0000269|PubMed:26388029, ECO:0000269|PubMed:9806842}; AltName: Full=Deubiquitinating enzyme 1; Short=hUBP; AltName: Full=Ubiquitin thioesterase 1; AltName: Full=Ubiquitin-specific-processing protease 1; Gene name Name=USP1 Encoded on Name=USP1 Keywords Autocatalytic cleavage; Complete proteome; DNA damage; DNA repair; Hydrolase; Nucleus; Phosphoprotein; Protease; Reference proteome; Thiol protease; Ubl conjugation; Ubl conjugation pathway. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AB014458; BAA34703.1; -; mRNA EMBL AF117386; AAD11441.1; -; mRNA EMBL AL117575; CAB55999.1; -; mRNA EMBL AL117503; CAB55967.1; -; mRNA EMBL AB208893; BAD92130.1; ALT_FRAME; mRNA EMBL CH471059; EAX06585.1; -; Genomic_DNA EMBL CH471059; EAX06586.1; -; Genomic_DNA EMBL BC050525; AAH50525.1; -; mRNA EMBL BC018745; AAH18745.1; ALT_SEQ; mRNA EMBL BC032364; AAH32364.1; ALT_SEQ; mRNA CCDS CCDS621.1; -; . PIR T17309; T17309; . RefSeq NP_001017415.1; NM_001017415.1; . RefSeq NP_001017416.1; NM_001017416.1; . RefSeq NP_003359.3; NM_003368.4; . UniGene Hs.35086; -; . ProteinModelPortal O94782; -; . SMR O94782; -; . BioGrid 113241; 57; . DIP DIP-53609N; -; . IntAct O94782; 34; . MINT MINT-4719170; -; . STRING 9606.ENSP00000343526; -; . BindingDB O94782; -; . ChEMBL CHEMBL1795087; -; . GuidetoPHARMACOLOGY 2428; -; . MEROPS C19.019; -; . iPTMnet O94782; -; . PhosphoSitePlus O94782; -; . BioMuta USP1; -; . OGP O94782; -; . EPD O94782; -; . MaxQB O94782; -; . PaxDb O94782; -; . PeptideAtlas O94782; -; . PRIDE O94782; -; . DNASU 7398; -; . Ensembl ENST00000339950; ENSP00000343526; ENSG00000162607; . Ensembl ENST00000371146; ENSP00000360188; ENSG00000162607; . GeneID 7398; -; . KEGG hsa:7398; -; . UCSC uc001daj.3; human; . CTD 7398; -; . DisGeNET 7398; -; . GeneCards USP1; -; . H-InvDB HIX0159950; -; . HGNC HGNC:12607; USP1; . HPA HPA028387; -; . HPA HPA028440; -; . MIM 603478; gene; . neXtProt NX_O94782; -; . OpenTargets ENSG00000162607; -; . PharmGKB PA37233; -; . eggNOG KOG1864; Eukaryota; . eggNOG ENOG410XQ81; LUCA; . GeneTree ENSGT00850000132276; -; . HOVERGEN HBG017288; -; . InParanoid O94782; -; . KO K11832; -; . OMA EYRASEI; -; . OrthoDB EOG091G04D9; -; . PhylomeDB O94782; -; . TreeFam TF331057; -; . Reactome R-HSA-110314; Recognition of DNA damage by PCNA-containing replication complex; . Reactome R-HSA-6783310; Fanconi Anemia Pathway; . ChiTaRS USP1; human; . GeneWiki USP1; -; . GenomeRNAi 7398; -; . PRO PR:O94782; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000162607; -; . CleanEx HS_USP1; -; . ExpressionAtlas O94782; baseline and differential; . Genevisible O94782; HS; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc; . GO GO:0008233; F:peptidase activity; EXP:Reactome; . GO GO:0004843; F:thiol-dependent ubiquitin-specific protease activity; IDA:UniProtKB; . GO GO:0042769; P:DNA damage response; detection of DNA damage; TAS:Reactome GO GO:0036297; P:interstrand cross-link repair; TAS:Reactome; . GO GO:0035520; P:monoubiquitinated protein deubiquitination; IMP:UniProtKB; . GO GO:0016579; P:protein deubiquitination; IDA:UniProtKB; . GO GO:0006282; P:regulation of DNA repair; IDA:UniProtKB; . GO GO:0009411; P:response to UV; IDA:UniProtKB; . GO GO:0001501; P:skeletal system development; IEA:Ensembl; . GO GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro; . CDD cd02671; Peptidase_C19O; 1; . InterPro IPR001394; Peptidase_C19_UCH; . InterPro IPR033815; USP1; . InterPro IPR018200; USP_CS; . InterPro IPR028889; USP_dom; . Pfam PF00443; UCH; 1; . PROSITE PS00972; USP_1; 1; . PROSITE PS00973; USP_2; 1; . PROSITE PS50235; USP_3; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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